Viral checkmate
نویسندگان
چکیده
منابع مشابه
CheckMATE
In der produzierenden Industrie – insbesondere in der Pharma-, Automobilund Zulieferindustrie – steigen die Qualitätsanforderungen in Richtung Null-Fehler-Produktion. Als Antwort kommen zunehmend automatische Verfahren zur Fehlerbehebung und Fehlervermeidung in der Produktionskette zum Einsatz. Integrierte Qualitätsund Prozessdaten von Sensorsystemen und Anlagensteuerungen stellen hierfür die B...
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Ligand-binding epitopes of proteins can mutate rapidly, as shown by viral mutations that lead to escape from neutralizing antibodies. We have undertaken to recreate in vitro the evolutionary competition between viral mutations that allow escape from antibody binding and host mutations that generate new neutralizing antibodies to the mutated viral antigen. To examine this vital race, we describe...
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DNA replication ensures accurate duplication of the original genetic information present in a cell in order for it to be properly transmitted to daughter cells. However, replication can be perturbed, for instance in rapidly dividing cancer cells, in a process referred to as replication stress (RS). Checkpoint kinase 1 (CHK1) is an essential component of the ATR-dependent DNA damage-response pat...
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It is difficult to overstate the profound impact that game theory has had on the economic approach and on the sciences more generally. For that reason, understanding how closely the assumptions that underpin game theoretic analysis conform to actual human decision-making is a question of first-order importance to economists. In this spirit, backward induction represents one of the most basic co...
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In the first three years of running, the LHC has delivered a wealth of new data that is now being analysed. With over 20 fb−1 of integrated luminosity, both ATLAS and CMS have performed many searches for new physics that theorists are eager to test their model against. However, tuning the detector simulations, understanding the particular analysis details and interpreting the results can be a t...
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ژورنال
عنوان ژورنال: Nature Methods
سال: 2007
ISSN: 1548-7091,1548-7105
DOI: 10.1038/nmeth0907-686